Broad Spectrum β-Lactamase Inhibition by a Thioether Substituted Bicyclic Boronate
نویسندگان
چکیده
منابع مشابه
Ribosomal Synthesis of Thioether-Bridged Bicyclic Peptides.
Many biologically active peptides found in nature exhibit a bicyclic structure wherein a head-to-tail cyclic backbone is further constrained by an intramolecular linkage connecting two side chains of the peptide. Accordingly, methods to access macrocyclic peptides sharing this overall topology could be of significant value toward the discovery of new functional entities and bioactive compounds....
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ژورنال
عنوان ژورنال: ACS Infectious Diseases
سال: 2019
ISSN: 2373-8227,2373-8227
DOI: 10.1021/acsinfecdis.9b00330